Both tirzepatide and semaglutide mimic the hormone GLP-1, but tirzepatide also mimics another hormone, glucose-dependent insulinotropic polypeptide (GIP), and this may further contribute to weight loss
More specifically, rotating your injection site helps reduce the risk of skin problems, such as pitting, lumps, or thickened patches (aka lipodystrophy )
Who Might Benefit Tirzepatide may be most relevant for arthritis patients who: Have a BMI of 30 or above with symptomatic knee or hip osteoarthritis Have been told they need joint replacement surgery but want to try weight loss first Have both type 2 diabetes and inflammatory arthritis Have failed to lose enough weight through diet and exercise alone to meaningfully reduce joint symptoms Have improved CRP or other inflammatory markers alongside their joint disease Are looking for a medication that addresses multiple metabolic and inflammatory concerns simultaneously Tirzepatide isn't a direct treatment for arthritis and shouldn't replace disease-modifying therapies for rheumatoid arthritis or other autoimmune joint conditions
Can I take NAD+ on an empty stomach, or should I eat beforehand
Semaglutide is generally less expensive, but cost depends on insurance coverage, manufacturer programs, and whether you qualify for assistance